Pre-Treatment Instructions:


  • Consult your primary care physician If you have been diagnosed with Pernicious Anemia.
  • In order to minimize the potential of bleeding/bruising, avoid aspirin & aspirin-containing medications for 5 days prior to injection.
  • Drink at least 16 oz of water before treatment.
  • Eat a meal before your treatment in order to keep your blood sugar stable during your treatment.
  • Notify your provider if you have a needle phobia so they can take proper precautions.
  • Notify your provider if you are pregnant or breastfeeding.

Post-Treatment Instructions:


  • Optimal results are achieved when treatments are continued routinely.
  • B12 injections can cause nausea, dizziness, and headaches when injected into the muscle. Contact your provider if the symptoms do not resolve within 24 hours.
  • Drink at least 24 oz of water after treatment.
  • Itching and/or a feeling of swelling throughout the body may occur. Consult your provider promptly if the effects persist.
  • Typically patients experience positive effects from the injection between 24-72 hours after treatment. 
  • Avoid alcohol for 48 hours after treatment.
  • Avoid strenuous exercise for 48 hours after your treatment.
  • Avoid touching the injection site for 6 hours after your treatment. You may experience a dull ache at the injections site for around 1 hour after your treatment.